Laser tattoo removal at mondello medical spa consists of light energy penetrating the epidermis and dermis layers of the skin to directly contact unwanted tattoo ink. the tattoo ink deep within the skin is heated and quickly shattered by the nanosecond technology of the lasers used.. Tattoos are no longer permanent but removal can be a long and costly business ridding yourself of a tattoo is now possible with laser and injectable therapies or even surgery.. Tattoo size, in dimensions, is the biggest factor that affects the cost of tattoo removal. most clinics will measure the height and width of your tattoo and either calculate the square inches, or compare it to a size categories chart..